All Publications

N6-Methyldeoxyadenosine: a new epigenetics mark in eukaryotes?

Luo, G-Z, Blanco MA, Greer EL, He C, Shi Y (2015).  Nature Reviews Molecular Biology, 16 (705-710).

 

DNA methylation on N(6)-Adenine in C. elegans (2015).

Greer EL*, Blanco MA*, Sendinc E, Aristizábal-Corrales D, Liu J, Gu L, Aravind L, He C, ShiY (2015).  Cell, 161(4): 868-78. (Cover article). *Denotes equal contribution

 

The histone chaperone CAF-1 safeguards somatic cell identity during transcription factor-induced reprogramming (2015).

Cheloufi S, Elling U, Hopfgartner B, Jung Y, Murn J, Badeaux A, Blanco A, Ang CE, Tennen D, Ferrari F, Wesche D, Abazova N, Hogue M, Tasdemir N, Rathert P, Vidal S, Fellner M, Wenzel D, Zinner M, Stadtfeld M, Almouzni G, Lowe SW, Rinn J, Wernig M, Shi Y, Park P, Penninger JM, Zuber J, Hochedlinger K (2015).  Nature, 528 (75281):218-24.

 

A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response.

Alpatov R, Lesch BJ, Nakamoto-Kinoshita M, Blanco MA, Chen S, Stutzer A, Armache KJ, Simon MD, Ali M, Murn J, Prisic S, Kutateladze TG, Vakoc CR, Kingston RE, Fischle W, Warren ST, Page DC, Shi Y (2014).  Cell, 157(4):869-81.

 

PKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasis .

Zheng H, Shen M, Zha YL, Li W, Wei Y, Blanco MA, Ren G, Zhou T, Storz P, Wang HY, Kang Y (2014).  Cancer Cell 26(3):358-73.

 

MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors.

Wan L, Lu X, Yuan S, Wei Y, Guo F, Shen M, Yuan M, Chakrabarti R, Hua Y, Smith HA, Blanco MA, Chekmareva M, Wu H, Bronson RT, Haffty BG, Xing Y, Kang Y (2014).  Cancer Cell 26(1): 92-105.

 

ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling.

Chakrabarti R, Wei Y, Hwang J, Hang X, Blanco MA, Choudhury A, Tiede B, Romano RA, DeCoste C, Mercatali L, Ibrahim T, Amadori D, Kannan N, Eaves CJ, Sinha S, Kang Y (2014).  Nature Cell Biology 16(10):1004-15.

 

A quantitative atlas of histone modification signatures from human cancer cells.

LeRoy G, DiMaggio PA, Chan E, Zee BM, Blanco MA, Bryant B, Flaniken IZ, Liu S, Kang Y, Trojier P, Garcia BA (2013). Epigenetics Chromatin 6(1).

 

Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2.

Chakrabarti R, Hwang J*, Blanco MA*, Wei Y, Lukačišin M, Romano RA, Smalley K, Liu S, Yang Q, Ibrahim T, Mercatali L, Amadori D, Haffty BG, Sinha S, Kang Y (2012).  Nature Cell Biology 14(11): 1212-22. *Denotes equal contribution

 

Global secretome analysis identifies novel mediators of bone metastasis.

Blanco MA, LeRoy G, Khan Z, Alečković M, Zee B, Garcia BA, Kang Y (2012).  Cell Research 22(9): 1339-55. (Cover Article)

 

Proteogenomic characterization and mapping of nucleosomes decoded by Brd and HP1 proteins.

Leroy G, Chepelev I, Dimaggio PA, Blanco MA, Zee BM, Zhao K, Garcia BA (2012).  Genome Biology 13(8): R68.

 

Identification of Staphylococcal nuclease domain containing 1 (SND1) as a Metadherin-interacting protein with metastasis- promoting functions.

Blanco MA, Aleckovic M, Hua Y, Xu Z, Wei Y, Kang Y (2011).  J Biol Chem, 286(22): 19982-92.

 

Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization.

Korpal M, Ell BJ, Buffa FM, Khan Z, Blanco MA, Hua Y, Hu G, Garcia BA, Singh M, Harris AL, Kang Y (2011).  Nat Med, 17(9): 1101-8.

 

Signaling pathways in breast cancer metastasis — novel insights from functional genomics.

Blanco MA and Kang Y (2011).  Breast Cancer Res, 13(2): 206-214.

 

Genomic gain of 8q22 activates metadherin and promotes chemoresistant metastasis of poor-prognosis breast cancer.

Hu G, Yang Q, Chong RA, Wei Y, Blanco MA, Li F, Haffty B, Reiss M, Kang Y (2009).  Cancer Cell, 15(1): 9-20. (Cover Article)

 

Extracellular matrix activity and caveolae events contribute to cell surface receptor activation that leads to MAP kinase activation in response to UV irradiation in cultured human keratinocytes.

Wang Q, A Turlington, S Heo, A Blanco, J Tian, Z Xie, BF Yan, YS Wan (2005). Int J Mol Med 15 (4), 633-640.

 

Maximum longevities of chemically protected and non- protected fishes, reptiles, and amphibians support evolutionary hypotheses of aging.

Blanco, MA and Sherman, P.W. (2005).  Mech Ageing Dev 126, 794-80.